Real science

Summer is here, and with it comes longer days, brighter skies, and a natural pull to get outside and soak up the good vibes. It’s the perfect season to step back from screens, slow down the scroll, and reconnect with real experiences, deeper joy, and immersing yourself in nature. But let’s be honest: in a world buzzing with notifications and digital noise, that kind of reset isn’t always easy.  Is Your Brain Overstimulated? If you wake up foggy, power through the day on coffee and scrolling, and crash into bed feeling drained, then take this 45 second quiz to help you identify if your dopamine system might be out of sync. Symptoms like low motivation, mood swings, restless sleep, and screen fatigue are all signs that your reward system may need a reset. That’s where the Do’Mo 12-Day Dopamine Reset comes in.  The Dopamine Crisis: Why You Need A Reset! Dopamine is a key neurotransmitter involved in motivation, focus, reward, and emotional resilience. Often described as the brain’s “pleasure chemical,” its role extends far beyond fleeting moments of joy, it underpins your drive to chase goals, enjoy achievements, and seek out pleasurable activities. Your brain releases dopamine when you experience something rewarding, whether it’s a delicious meal, an exciting event, or completing a task. Yet in a world saturated with fast, intense dopamine hits from constant notifications to binge-worthy content or getting wired on stress, caffeine, sugar and alcohol, our dopamine system can become overstimulated and dysregulated. Over time, this can make it harder to find fulfillment in everyday experiences, leading to reduced motivation, mental fatigue, and a persistent sense of dissatisfaction. The solution? A dopamine reset!  Less Scroll, More Soul: A Fresh Take on Wellness A dopamine reset isn’t about denying yourself pleasure, it's about restoring balance. It’s an intentional pause from the over-stimulation of modern life, designed to help you reconnect with slower, more sustaining sources of joy: the calm of nature, the rhythm of movement, the depth of real connection. When dopamine is rebalanced, focus sharpens, energy returns, sleep improves and even the simplest moments begin to feel enriching and fulfilling again. The 12-Day Dopamine Reset: A Journey to Rebalance The 12-Day Dopamine Reset is a thoughtfully designed roadmap to restoring dopamine balance with 12 easy lifestyle hacks that guide you through a digital detox and encourage you to engage with mindful activities to reawaken your capacity for deep, lasting enjoyment. This step-by-step plan is packed full of practical tips, accessible tools and daily practices to help you: Identify your dopamine disruptors: Gain clarity on the activities and habits that may be contributing to an imbalance. Create a mindful routine: Incorporate practices like breathwork, meditation, journaling, and spending time outdoors. Reconnect with your senses: Rediscover the pleasure in tastes, smells, sounds, and textures. Set realistic goals: Implement intentional changes that align with your lifestyle, no extremes, just steady shifts that stick. Daily Sundowner: The Neuroscience Inside The Can The 12-Day Dopamine Reset includes a Do’Mo Variety Pack containing 12 Zero Proof Elixirs (4 of each flavor). Each can is packed with 6000mg of 17 functional ingredients, including natural nootropics, amino acids, and nutrients that work synergistically to support dopamine balance. During the Dopamine Reset, each evening begins with a Do’Mo Zero-Proof Elixir, the time of day when you might typically reach for a glass of wine or something sweet. Whether winding down solo or heading out to socialize, this functional sundowner hack provides a gentle lift, promotes relaxation, and enhances your overall mood – without the alcohol, added sugar, or caffeine. The Zero Proof Elixirs complement the reset program beautifully, offering a flavorful and enjoyable alternative to less healthy evening habits.   Begin Your 12-Day Transformation This summer, recalibrate. Step away from the over-stimulation of modern life and return to a more intentional rhythm that improves your vitality and mood. The 12-Day Dopamine Reset, paired with Do’Mo’s functional elixirs, offers a natural and healthy approach to wellbeing, rooted in neuroscience, guided by nature, and designed for real life. With every thoughtful sip and each mindful shift, you are nourishing your neurochemistry, lifting your mood, rebuilding motivation and awakening a deeper sense of presence. Your most vibrant summer starts here. Click here for the 12-Day Dopamine Reset 

Biohacking. It sounds intense, like something reserved for tech bros, futurists, or people who wear glucose monitors for fun. But strip away the buzzword, and you’re left with a simple, powerful, wellness concept: the pursuit of better living through intentional, data-driven choices. At its core, biohacking is about optimizing the human body and brain. Fueling performance, promoting longevity, and feeling your absolute best from dawn to dusk. Whether that means tracking deep sleep with an Oura Ring, experimenting with intermittent fasting, infrared saunas or swapping cocktails for nootropic elixirs (hello Do’Mo!), the biohacker’s toolkit is ever-evolving. And that’s exactly why so many in the biohacking space are falling head over heels for Do’Mo—the fun, functional, alcohol-free way to upgrade your happy hour without compromising your health. One thing biohackers are known for? Uncovering products that actually work. So it’s no surprise that Do’Mo’s unrivaled 6000mg dose of 17 functional ingredients stops many a biohacker in their tracks, usually followed by a jaw-dropping, “Wait… is this for real?” Yes, it’s real. Do’Mo is backed by science and delivers real results, supporting mood, sleep, and mental clarity with nothing but clean, bioactive ingredients available in three great flavors.  But before we dive into what makes Do’Mo the biohacker’s dream social tonic. Let’s take a quick look at the pillars that guide this health-optimizing movement. What Is Biohacking, Anyway? Biohacking is the art and science of enhancing your biology through strategic lifestyle interventions. It’s about learning how your body works, and then giving it what it needs to perform better, longer, and more efficiently. Think of it like this: Biohackers track, test, and tweak their inputs (food, sleep, movement, supplements, etc.) They use both ancient wisdom and modern tech to fine-tune their internal systems And they chase sustainable energy, brainpower, and vitality like it’s a sport For beginners, this might start with cutting down on sugar or starting your day with a Dave Asprey Bulletproof Coffee to rev up your metabolism. For advanced hackers, it can mean stacking nootropics, red light therapy, or the Wim Hof Method cold exposure to dial up peak performance. But across the spectrum, six common values unite biohackers—and each hack points straight to why Do’Mo is such a hit. Hack 1: Low-to-No Alcohol: Protect the Cells, Protect the Brain Contrary to popular belief, most biohackers aren’t totally sober. But they are extremely selective about alcohol use. Why? Because alcohol is a known neurotoxin and pro-aging agent—plain and simple. Even moderate drinking contributes to oxidative stress, impairs sleep, disrupts hormone balance, and damages cellular structures like DNA and mitochondria. Long-term, it shrinks brain volume and increases risk for neurodegenerative disease. That’s a hard pass for people trying to live to 100 with their wits intact. Do’Mo and hack 1? Our Zero Proof Elixirs offer biohackers a new kind of nightlife. One that lets you stay social without paying the biological price. You still get the ritual, the glass in hand, the mellow mood... but you wake up in brainpower mode, not hangover mode. Plus, no sketchy ingredients. No jitters.. Just good vibes, backed by functional nutrition. Hack 2: Mood Optimization: Feel-Good Vibes, Every Single Day For biohackers, it’s not enough to just look healthy—they want to feel amazing too. Mood matters. Emotional resilience, motivation, and daily joy are all seen as signs of a well-regulated, high-performing system. That’s why many biohackers focus on neurotransmitter balance, the delicate interplay between brain chemicals like dopamine, serotonin, and GABA that influence everything from motivation and reward to calm and contentment. Do’Mo and hack 2? Do’Mo is designed to support natural mood elevation through amino acids that replenish these neurotransmitter pathways: L-Glutamine – A precursor to GABA, supports calm and gut-brain balance GABA – Helps regulate anxiety and promote mental ease L-phenylalanine & NALT (N-acetyl L-tyrosine) – Precursors to dopamine, the motivation and focus neurotransmitter Mucuna pruriens – Naturally rich in L-DOPA, a direct dopamine precursor 5-HTP – Supports serotonin synthesis, the neurotransmitter tied to happiness and well-being Together, these nootropic functional ingredients help create a calm, uplifted mental state—supporting ease, connection, and confidence while you socialize. The result? You feel genuinely good in the moment, without the crash or cloud the next day. Hack 3. No Refined Sugar: Because Aging Starts at the Cellular Level Sugar is the ultimate anti-biohack. Refined sugar spikes insulin, triggers inflammation, and accelerates a process called glycation—where excess glucose binds to proteins and fats, damaging cells and aging tissues prematurely (including skin, organs, and the brain). It’s not just about blood sugar and waistlines anymore. Biohackers are ditching sugar to slow biological aging, improve metabolic health, and boost cognitive resilience. Do’Mo and hack 3? You won't find any added sugar in a can of Do’Mo. The delicious sweet taste comes from natural sources including stevia, erythritol and a very small amount of grape juice. Instead of sugar and stimulants it’s bioactive forms of vitamins (niacinamide,calcium pantothenate, pyridoxal-5-phospate, magnesium ascorbate) and zinc gluconate that power up your energy and metabolism for an uplifting experience. No sugar, no energy crash, plus Do’Mo also includes magnesium (as Magtein®) and L-theanine that promote a calm relaxed mood, so your body can wind down or perk up, naturally. Hack 4. 100% Natural Ingredients: No Junk, No Toxins, No BS Biohackers scrutinize ingredient lists like scientists because they understand that what you put in your body becomes your biology. Synthetic additives, preservatives, and artificial flavors? Those are red flags. Instead, they seek clean, natural formulations designed to support the body's innate intelligence. Do’Mo and hack 4? Every can of Do’Mo is crafted with integrity—no artificial sweeteners, synthetic colors, or sketchy fillers. Just natural nootropics, botanical extracts, amino acids, and nutrients that work with your body. Even the natural flavorings are from original source materials. Hack 5. Sleep Is Sacred: Biohackers Protect Their Nights Sleep isn’t just recovery—it’s where regeneration happens. It’s when your brain consolidates memory, your body clears cellular waste, and hormones reset. Poor sleep, or alcohol-disrupted sleep, is a performance liability for any biohacker. That’s why so many go to great lengths to optimize their nights with blue light blockers, cooling mattresses, magnesium supplements, and screen curfews. Do’Mo and hack 5? Unlike social beverages that rev you up or leave you wired, Do’Mo’s functional ingredients support your natural wind-down so you can transition seamlessly from social to sleep mode with functional ingredients including  Magtein® (magnesium L-threonate) – Enhances brain magnesium levels and sleep quality L-theanine – Found in green tea, promotes meditative alpha brain waves and relaxation without drowsiness GABA – Calms the nervous system and eases stress responses So when you come home from a night out, you’re already primed for deep, restorative sleep. Hack 6: Brain Power & Cognitive Longevity: Think Sharp, Stay Sharp Ask any serious biohacker and they’ll tell you that mental performance is non-negotiable. They want to be clear, creative, focused, and keep that edge as they age. That’s why nootropics and cognitive enhancers are central to most stacks. Do’Mo and hack 6?  Do’Mo includes ingredients that directly support cognitive function, clarity, and mood regulation, so you’re not just avoiding a hangover, you’re boosting your brain to be ready for action from the moment you wake up. . Cognizin® (citicoline) – A clinically studied nootropic that supports focus, attention, and memory Vitamin B5 (pantothenic acid) – Supports acetylcholine production, mental performance and stress resilience Zinc gluconate – Essential for neurotransmitter activity, cognitive function and mental clarity This is why people are swapping their Friday night cocktails for Do’Mo—and still showing up sharp on Monday morning. Biohacking Is a Lifestyle—Do’Mo Makes It More Fun The real reason Do’Mo is making waves in the biohacking community? It’s not trying to replace fun with function—it merges the two seamlessly. You get to enjoy your rituals. To say yes to connection, flavor, and the buzz of the moment, without the metabolic chaos or neurological fallout. Whether you’re just starting to experiment with health optimization or you’re deep in the world of Oura data and NAD+ patches, Do’Mo meets you at the level you are at.. And you won’t be alone. Do’Mo has been spotted at wellness centers, day raves, flow retreats, and biohacking meetups across the country. Come and Sample Do’Mo at the Next Biohacking Events  Want to dive deeper? Come sample the three Do’Mo flavors and meet founder Philip Gladman and Food Scientist Susie Perry at these biohacking events in 2025. Explore these cutting-edge hubs of the biohacking world: Blohacking Expo - Miami 28th Feb to 1st March 2025 Health Optimization Summit - Austin 11th and 12th April 2025 Dave Asprey’s Biohacking Conference - Austin 28th to 30th May 2025 Try Do’Mo. Hack Your Happy Hour. Whether your goal is sharper focus, deeper sleep, or simply living longer and better—Do’Mo is here to support your adventures. With zero alcohol, zero added sugar, and 100% natural ingredients that love your brain and body, it’s no wonder biohackers are making the switch. So the next time you reach for a drink…Make it a smart one. Make it Do’Mo.  

Ever wondered why some social situations feel like magic while others just make you want to bail early? It’s not just about the people, the playlist, or the venue—it’s about the chemistry in your brain. Literally. Your mood, energy, confidence, and ability to connect all come down to neurotransmitters—tiny chemical messengers that run the show behind the scenes. Understanding how they work (and how to support them) is the key to shifting from fight-or-flight to stay and play mode. Let’s take a peek inside the brain—and break down the feel-good science behind Do’Mo. What Are Neurotransmitters? Neurotransmitters are chemical messengers that help your brain cells (neurons) talk to each other. They carry signals across tiny gaps called synapses, allowing your brain and body to sync up thoughts, emotions, movements, and reactions. Different neurotransmitters create different effects—some calm you down, others lift your mood, and a few even drive motivation or social bonding. Where Are They Made? Most neurotransmitters are made from special proteins (amino acids) and nutrients in your diet. They’re synthesized in the brain (often in the limbic system, which handles mood and memory), but some are also produced in the gut—hello, serotonin! When it comes to different social scenarios, it’s mainly dopamine, serotonin, GABA, oxytocin, and endorphins that shape the landscape.  Here’s where your brain’s chemical squad comes in: Dopamine: Made in the midbrain (substantia nigra and ventral tegmental area); drives motivation, reward, pleasure. Serotonin: Made in the brainstem (raphe nuclei) and the gut; regulates mood, sleep, and emotional stability. GABA: Made throughout the brain; acts as the brain’s main calming agent. Oxytocin: Produced in the hypothalamus and released by the pituitary gland; promotes trust, bonding, and social warmth. Endorphins: Produced in the hypothalamus and pituitary gland; these natural opioids are released in response to stress, exercise, laughter, and even music. They ease pain, elevate mood, and create that euphoric “high". How Neurotransmitters Your Shape Behavior  Neurotransmitters are the ultimate mood DJs. They set the vibe for your thoughts, feelings, and actions. Each one plays a distinct role in how you experience the world, especially in social situations. Dopamine is your inner hype squad. It fuels your drive to chase goals, take risks, and seek out rewarding experiences. It’s what lights up when you spot your crush across the room or finally hit the chorus of your favorite song.  Serotonin helps you keep your cool—it regulates mood, sleep, appetite, and that all-important sense of emotional stability. When your serotonin levels are balanced, you feel more grounded and resilient.  GABA, the brain’s primary calming neurotransmitter, acts like a built-in chill pill. It reduces mental noise and overstimulation, making it easier to stay relaxed, even in busy or unfamiliar settings. Oxytocin, the social glue. It promotes trust, closeness, and connection—it’s what makes eye contact with a friend across the table feel warm and affirming.  Endorphins, let’s not forget your body’s natural painkillers. Released during laughter, movement, or physical touch, they ease tension and create that euphoric, floaty “life is good” sensation. How Your Environment Stimulates Your Brain Chemistry The environment you put yourself in—your surroundings, people, music, smells, even the lighting—sends constant signals to your brain. These signals can either turn on feel-good neurotransmitters or elevate your, stress hormones. The more positive signals your brain receives (safe vibes, good company, sensory comfort), the more it says, "Yes, this is good—let’s stay here." The more negative or unfamiliar signals it receives, the more it says, "Nope, abort mission." What happens on a good night out? Imagine the perfect night out. You walk into your favorite bar or venue. Your best friend’s already at the table. Your song comes on. The lighting is warm. You’re wearing something that makes you feel good. Boom! Your brain lights up like a fireworks show. Dopamine kicks in as your brain rewards you for being somewhere pleasurable. Serotonin rises because you feel safe and emotionally steady. GABA keeps everything calm and easygoing, even if the place is packed. Oxytocin flows as you laugh and connect with your crew. Endorphins surge when you dance, sing, or move your body, layering in that fizzy, feel-good buzz. Your brain stores this moment as a “yes, more of this” memory, so you’re more likely to repeat it and feel drawn to those vibes again. How does stress mess with your good vibes? Now imagine you’ve had one of those days. Your body’s on edge, you feel tired and depleted and irritable. You're in unfamiliar surroundings, the music is all out of tempo and you're generally feeling unimpressed and uninspired. In this case, your brain doesn’t release the happy messengers—it triggers cortisol, your main stress hormone. Cortisol activates the fight-or-flight response, making your heart race, your muscles tense, and your mind hyper-alert. This ancient survival mode is great for escaping saber-toothed tigers—not so great for mingling at a dinner party or waiting to get served at the bar.  Social anxiety, low mood, lack of confidence, and low self-esteem can all push your brain into this stress state, even in neutral or mildly stressful environments, making socializing feel like a threat, instead of a treat. How Do’Mo Helps You Shift Gears When your brain is in stress mode, it’s hard to “think” your way out of it. You need nervous system support, and that’s where functional ingredients come in. Here’s how the science of Do’Mo helps you go from fight-or-flight to stay-and-play. From the 17 functional ingredients in every can of Do’MO, there are five key players that help turn down stress and power up positive vibes: L-Theanine an amino acid found naturally in green tea) promotes alpha brain waves, enhancing focus and calm without sedation. It helps raise GABA and dopamine levels naturally, making it easier to be present and socially engaged. GABA works directly as a calming neurotransmitter. It dials down overactivity in the brain, helping you ease into the moment with less tension. 5-HTP is a direct precursor to serotonin. It supports mood balance, emotional resilience, and that centered, stable feeling that makes socializing enjoyable. Mucuna pruriens provides natural L-Dopa, the building block of dopamine. It supports motivation, reward processing, and that inner spark that makes you want to connect and explore. Magtein® (magnesium L-threonate) crosses the blood-brain barrier to boost magnesium in the brain. Magnesium regulates the stress response and supports neuroplasticity (aka, your brain’s ability to rewire itself for better moods and memories). Together, these ingredients help recalibrate your nervous system, so you're not just reacting to your environment; you’re co-creating the vibe. Fuel the Feelings You Want You don’t have to force a good time, you just need to give your brain what it needs to feel safe, supported, and socially synced. Whether you're heading out with friends, navigating a first date, or just trying to feel more at ease in your own skin, let your neurotransmitters lead the way. By creating the right internal environment—and supporting it with science-backed ingredients like those in Do’Mo—you start to shift the chemistry, shift the moment, and shift your entire experience. Because when your brain’s vibing, everything else falls into place.